Resident Evil Requiem Weapons: All Locations and Unlock Priorities

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Resident Evil Requiem splits its weapons between survival pressure and firepower

The key thing to know before hunting Resident Evil Requiem weapons is that Grace Ashcroft and Leon S. Kennedy do not build arsenals the same way. LootStrategist’s weapon guide describes Grace’s loadout as survival-focused, with storage chest management and no standard Leon-style upgrade track, while Leon’s side of the campaign uses Supply Boxes for purchases, upgrades, ammunition, and gear.

That split creates the main tension behind Resident Evil Requiem all weapons completion. Some weapons are story handouts, some sit in optional rooms you can pass under pressure, some are tied to Leon’s economy, and the strongest toys sit behind Special Content or Insanity difficulty. If you are trying to follow how to unlock weapons in Resident Evil Requiem without spoiling every encounter, think of the arsenal in four lanes: Grace’s Care Center survival kit, Leon’s campaign finds, Leon’s Supply Box purchases, and post-game or challenge unlocks.

The guide sources supplied for this piece agree on the broad structure of the roster. LootStrategist lists the campaign weapons, three Supply Box firearms, eight Special Content weapons, and a separate Insanity-only R.I.P. Knife. Vandal’s guide, published August 10, 2026, also frames the arsenal around Grace and Leon, with unavoidable spoilers for weapon acquisition. The exact balance value of each weapon is partly guide interpretation, so this piece separates listed unlock locations from practical priority calls.

How the inventory systems change your unlock order

Grace’s weapons matter most when they reduce panic, not when they inflate damage numbers. According to LootStrategist, Grace can place weapons in safe-room storage chests, but her standard weapons do not use Leon’s upgrade system. Vandal describes her Makeshift Knife as a defensive tool meant to help when an infected enemy grabs her, not as a serious direct-damage option. That is the pattern for much of Grace’s side: the right weapon at the right moment buys breathing room in a game built around scarcity, audio cues, and hostile corridors rather than constant shooting.

Leon plays a different game. LootStrategist says Leon cannot store weapons the same way Grace does, but his Supply Boxes allow him to buy weapons, ammunition, upgrades, and gear. Weapons he sells can later be purchased again, which gives him more flexibility when inventory space tightens. The same source says compatible Leon weapons can normally be upgraded through Supply Boxes, and that Advanced Tuning opens after destroying all 25 Mr. Raccoon memoriams.

For first-run planning, that means Grace’s priority is retrieval and coverage. Do not leave her early handgun recovery or defensive blades behind if you can safely route them. Leon’s priority is role coverage and upgrade discipline. A shotgun, a rifle, and a reliable sidearm tend to change far more fights than buying every option the moment a Supply Box offers it.

Grace’s campaign weapons: where to look before the Care Center closes in

Grace’s listed first-playthrough weapons are the S&S M232, B934, Requiem, Makeshift Knife, and Hunting Knife. LootStrategist places the S&S M232 in the Care Center West Wing, 2F, Bar & Lounge. Vandal adds more progression context, saying Grace starts with the S&S M232, loses it as part of the story, and can recover it during Patient Center (III) after access to the west wing, specifically in the northwestern corner of the Bar and Lounge, in the sink behind the counter. That makes it one of the most important early recoveries, because missing it leaves Grace leaning harder on evasive play and expendable tools.

LootStrategist lists the B934 as a Grace weapon found in the Care Center Dining Room. The provided source text does not include deeper stats or a puzzle requirement for it, so treat the Dining Room as a priority sweep when the route opens rather than assuming the weapon will be handed to you. In Resident Evil terms, dining spaces are rarely quiet for long, so clear your inventory before committing to a return trip.

The Requiem is obtained through story progression, according to both LootStrategist and Vandal. The Resident Evil Wiki’s Requiem magnum page identifies it as a DSO-issued, extremely powerful magnum revolver using 12.7x55mm rounds, with an inventory description emphasizing high power and piercing capability. The same wiki description notes the weapon is demanding to handle despite design features intended to reduce recoil. For spoiler-light planning, the practical note is simple: save its shots for moments that feel designed to end a debate, because the sources frame it as a high-impact weapon rather than routine hallway insurance.

Grace’s Makeshift Knife is listed by LootStrategist as found in the Care Center Filing Room, with additional copies available through finding or crafting. Vandal says several appear throughout the game and stresses that it is primarily a defensive item for escaping grabs, not a weapon for sustained melee. LootStrategist also lists the Hunting Knife as dropped by an enemy near the Dining Room and Filing Room. Between the two, the Makeshift Knife is the panic button, while the Hunting Knife is the one to watch for when the game pushes you through that Dining Room and Filing Room pocket.

Leon’s campaign weapons: the route from starting gear to heavy answers

Leon begins with the Hatchet and the Alligator Snapper, according to LootStrategist’s quick reference. Those starting tools establish his half of Requiem as more directly combative than Grace’s, but the early campaign finds are still worth routing carefully because Leon’s inventory cannot be offloaded into Grace-style storage.

LootStrategist lists the MSBG 500 in the Care Center Attic and the Classic 70 as a story progression weapon. Those two entries are useful milestones: one asks you to search an optional-feeling upper space, while the other arrives as part of the campaign. If you are trying to keep the route spoiler-light, remember the Attic callout. It is the kind of weapon location players miss when they are rushing out of a hostile building with low ammo and bad nerves.

Later Leon finds widen the arsenal. LootStrategist places the Gal in the East Raccoon City Underground Parking Garage, the Marksman 1A in BSAA Container 03, and the W870 Police at Gun Shop Kendo. WatchMojo’s ranking article adds a specific note for the Marksman 1A, saying it is inside BSAA Container #3 east of the Gas Station in East Raccoon City. WatchMojo also argues, as an opinion-based ranking, that the Marksman 1A is a major upgrade over the Classic 70 because of its semi-automatic action, larger magazine, faster reloads, and improved handling. That evaluation is not the same as an official stat sheet, but it matches the role you would expect from a weapon found in a more deliberate exploration pocket: it rewards players who slow down and search.

Mortal Edge is the one campaign-adjacent weapon with a more complicated listing. LootStrategist marks it as tied to the Commander boss and Special Content. That phrasing suggests you should not treat it like a normal room pickup. If you want every Resident Evil Requiem weapon location on a first file, keep a mental note that boss rewards and Special Content unlocks may overlap rather than living in a simple map checklist.

Supply Box firearms and Special Content weapons

Leon’s three listed Supply Box firearms are the Silencer 9, 990-TAC, and Stiri REVO3 A1. LootStrategist says all three are bought from Leon’s Supply Box system. The supplied source text does not give prices, chapter availability, or upgrade costs, so the safest advice is to inspect each Supply Box refresh before selling core guns. Since LootStrategist says sold weapons can be bought again later, Leon has some room to experiment, but every purchase still competes with ammunition, upgrades, and gear.

Special Content is where Requiem’s completion list gets louder. LootStrategist identifies Freya’s Needle for Grace, Kotetsu for Grace, Matilda IMP for Leon, Ghost Grudge for Leon, Redemption for Leon, Clatter Carbine for Leon, RPG-7 for Leon, and Mortal Edge for Leon as Special Content weapons. The source text does not specify the exact unlock currency or challenge conditions for each item, only that they belong to the Special Content system, so readers should treat them as post-game or bonus-menu targets rather than standard campaign scavenger finds.

WatchMojo’s opinion ranking gives two useful build notes for this bonus tier. It calls Kotetsu Grace’s strongest knife choice because, according to the article, it never breaks, removing the durability concern attached to disposable blades. It also highlights Redemption as a powerful one-shot handgun when paired with the Power Shades charm, arguing that every shot benefits from a last-bullet damage bonus because the weapon holds a single round. Those are ranking-based recommendations, not official unlock requirements, but they help explain which Special Content weapons may change your second-run planning first.

The RPG-7 sits in the list as the obvious overkill prize, but the supplied sources do not provide detailed unlock conditions or balance notes. Until you have the Special Content menu in front of you, prioritize unlocks that solve recurring survival problems: Grace’s permanent melee option, Leon’s flexible sidearms, and any weapon that supports infinite-ammo or challenge-run goals if those menus become available on your file.

The Insanity-only R.I.P. Knife and the weapons most players miss

The R.I.P. Knife is separate from the eight Special Content weapons in LootStrategist’s guide. It is listed as a Grace weapon unlocked as an Insanity-only Parlor reward. That distinction matters because it is easy to assume every bonus weapon comes from one shop or post-game screen. Based on the provided listing, the R.I.P. Knife is tied to difficulty and location, not simply to the Special Content pool.

The easiest campaign misses, based on the locations named in the sources, are Grace’s recovered S&S M232 in the Bar and Lounge, the B934 in the Dining Room, the Hunting Knife drop near the Dining Room and Filing Room, Leon’s MSBG 500 in the Care Center Attic, the Gal in the East Raccoon City Underground Parking Garage, the Marksman 1A in BSAA Container 03, and the W870 Police at Gun Shop Kendo. None of those are described in the supplied material as automatic story handouts. By contrast, Requiem and Classic 70 are listed through story progression, while Leon’s Hatchet and Alligator Snapper are starting weapons.

If you are playing with minimal spoilers, use area names rather than event names as your checklist. When the game opens the Care Center West Wing, sweep the Bar and Lounge. When Grace is routed around the Dining Room and Filing Room, watch for both a weapon pickup and an enemy drop. When Leon reaches bigger city spaces, search the underground parking garage, BSAA Container 03, and Kendo’s gun shop before pushing the plot forward. Requiem’s horror works because it makes every detour sound like a mistake, but the weapon list rewards the player who can stand still long enough to listen, breathe, and check the corners.

Complete spoiler-light weapon checklist

For quick reference, these are the Resident Evil Requiem all weapons entries supported by the supplied guide listings. Grace gets the S&S M232 in the Care Center West Wing 2F Bar and Lounge after story loss and recovery, the B934 in the Care Center Dining Room, the story-progressed Requiem, the Makeshift Knife from the Care Center Filing Room with more found or crafted, the Hunting Knife from an enemy drop near the Dining Room and Filing Room, Freya’s Needle through Special Content, Kotetsu through Special Content, and the R.I.P. Knife as an Insanity-only Parlor reward.

Leon starts with the Hatchet and Alligator Snapper. His campaign route includes the MSBG 500 in the Care Center Attic, Classic 70 through story progression, Gal in the East Raccoon City Underground Parking Garage, Marksman 1A in BSAA Container 03, W870 Police at Gun Shop Kendo, and Requiem through story progression when the weapon changes hands. His Supply Box purchases are Silencer 9, 990-TAC, and Stiri REVO3 A1. His Special Content weapons are Matilda IMP, Ghost Grudge, Redemption, Clatter Carbine, RPG-7, and Mortal Edge, with LootStrategist also tying Mortal Edge to the Commander boss.

The unlocks that matter first are the ones that stop a bad room from becoming a death loop. Recover Grace’s S&S M232 as soon as the Bar and Lounge route opens. Treat her knives as survival tools, especially before you have generous ammunition. For Leon, do not skip the Attic, parking garage, BSAA container, or Kendo location if you want full coverage before investing heavily in Supply Box experiments. After credits or challenge runs, start with Special Content weapons that change resource pressure, especially Kotetsu for Grace if WatchMojo’s durability note matches your version, then move into Leon’s high-damage bonus gear.